Endocrine Abstracts

Sex steroid hormones play a pleomorphic role in preservation of BMD. The BMD, the blood circulating 25-hydroxyvitamin D [25(OH)D], testosterone and estradiol levels may decline with age and to contribute to bone fragility. Low vitamin D is associated with increased falls number and fractures.Recently, a new software solution, 3D-SHAPER - allows measurements of both trabecular and cortical bone as well as 3D images -, it incorporates a model-bas...

Bone mass, macrostructure and lean mass are being identified as main contributors of strength of upper femur. The purpose of this study has been to assess the role of the cortical and trabecular bone as well as muscle mass in the hip fracture production. We used a new DXA application which allow 3D bone volume reconstruction from standard 2D DXA scans, providing a three dimensional approach of the femoral shape and bone density spatial distribution and measurement cortical thi...

Introduction: Patients suffering from acromegaly, despite normal or even higher bone mineral density (BMD), have prevalent vertebral fractures (VFs). Impaired bone microarchitecture is involved fragility fracture development, but vitamin D status could be involved in this impairment.Aim of the study: Comparison of bone parameters such as BMD, trabecular bone score (TBS) and 3D-SHAPER parameters in acromegaly patients according to level of 25(OH)D3.<p...